Concurrently, Gary Ruvkun investigated the regulation on the lin-14 gene in his recently recognized laboratory at Massachusetts Standard Healthcare facility and Harvard Medical School. As opposed to how gene regulation was then recognised to function, Ruvkun confirmed that it's not the creation of mRNA from lin-14 that is certainly inhibited by lin-4. The regulation appeared to happen at a later phase in the process of gene expression, from the shutdown of protein creation. Experiments also disclosed a segment in lin-fourteen mRNA which was essential for its inhibition by lin-four.
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"Su trabajo pionero sobre la regulación genética por microARN allanó el camino a investigaciones sobre terapias novedosas para enfermedades devastadoras como la epilepsia, pero también nos abrieron los ojos a la maravillosa maquinaria que controla estrechamente lo que ocurre en nuestras células", dijo a la BBC Janosch Heller de la Universidad de la Ciudad de Dublín.
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Es importante resaltar que el médico no trata enfermedades, sino que trata a las personas que las padecen, por ello recae sobre ellos un peso importante, pues este paciente es parte necesaria de una sociedad y la necesidad here de restituirlo a ella es lo principal.
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